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Will Isiah Pacheco play vs. Colts? Latest news on Chiefs RB in Week 12

2025-11-22 02:38
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Will Chiefs RB Isiah Pacheco play against the Colts in Week 12? Here's the latest update on Pacheco's status.

Will Isiah Pacheco play vs. Colts? Latest news on Chiefs RB in Week 12Story byChiefs WireJohn Dillon, Chiefs WireSat, November 22, 2025 at 2:38 AM UTC·1 min read

Running back Isiah Pacheco participated in all of the Kansas City Chiefs' practice sessions this week ahead of the team's matchup against the Indianapolis Colts on Sunday.

Will Pacheco take the field for Kansas City's Week 12 showdown with the Colts?

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Here is the latest on Pacheco's status:

Isiah Pacheco injury update

Pacheco is dealing with a knee injury, but managed to be a full participant in Kansas City's workouts on Wednesday, November 19. However, he was downgraded to a limited participant during the Chiefs' practices on Thursday and Friday.

He has officially been ruled out for Week 12.

How long will Isiah Pacheco be out?

While Pacheco won't take the field to face the Colts, his return to practice this week is an indication that he could be available for Kansas City's matchup against the Dallas Cowboys on Thanksgiving.

Chiefs RB depth chart

With Pacheco set to miss the Chiefs' matchup against Indianapolis, the Chiefs will rely on running backs Kareem Hunt, Brashard Smith, and Elijah Mitchell to carry their ground game against the Colts.

This article originally appeared on Chiefs Wire: Isiah Pacheco injury: Will Chiefs RB play vs. Colts in Week 12?

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