NFL Week 13 Monday Night Football predictions: Giants vs. Patriots odds, winners picks

Week 13 comes to an end with the New York Giants visiting the New England Patriots on Monday Night Football. The Giants are flirting with the first-overall pick in the 2026 NFL Draft as they enter the week with a 2-10 record. The Patriots are the top team in the AFC playoff picture and could be the first team to reach 11 wins this season, coming into the game with a league-best 10-2 mark.

As we do for every game during the season, our contributors are back with their straight-up winners picks for tonight’s game. If our contributors also make picks against the spread or the point total, you can see those predictions below as well.

You can also join us in making picks, now. All you have to do it sign up using the link in the banner on the widget at the end of the article. Thank you to Tallysight for setting us up with the widget and the new community picks option.

Week 13 Monday Night Football

All odds via FanDuel Sportsbook.

Spread: Patriots -7.5 Point Total: 46.5Moneyline: Giants +290 | Patriots -360

Week 13 Monday night Picks