Cowboys-Chiefs Final injury report: Pickens status, Pro-Bowl OL ruled out

The Dallas Cowboys and Kansas City have worked their short weeks as well as they can, and now it's time for them to try and feast on each other. With both teams coming off of Week 12 victories, the stage is set for a solid Thanksgiving Day matchup between the only two professional organizations to ever call Dallas home.

The Chiefs (6-5) come in looking to close the gap in the AFC West while the Cowboys (5-5-1) have longer hopes of becoming relevant in the NFC race. Both clubs are going to have to give it a go without important pieces that protect their highly paid and highly-regarded quarterbacks. Dak Prescott's blindside protector, left tackle Tyler Guyton will miss the contest after suffering an ankle sprain this past week. The same fate caught up with Patrick Mahomes' Pro Bowl right guard Trey Smith.

Second-year man Nate Thomas will replace Guyton for the Cowboys, while the Chiefs will roll with Mike Caliendo to replace Smith. The Chiefs will also be without Travis Kelce backup, Noah Grey (concussion), and cornerback Chris Roland-Wallace (back). Outside of that, the only non-IR player who has a concern is Dallas CB Caelen Carson, who tweaked his hamstring on Tuesday and is listed as questionable.

Here's a look at each team's full rundown.

Dallas Cowboys - OUT

• LT Tyler Guyton, Ankle

Dallas Cowboys - QUESTIONABLE

• CB Caelen Carson, Hamstring

Dallas Cowboys - NO DESIGNATION

• DE Jadeveon Clowney, Neck

• DE Dante Fowler, Shoulder

• Safety Malik Hooker/ Toe/Thigh

• DT Osa Odighizuwa, Elbow

• WR George Pickens, Knee/Calf

• WR Kavontae Turpin, Shoulder/Illness

• DT Solomon Thomas, Calf

• Safety Donovan Wilson, Neck

• CB DaRon Bland, Wrist

• DE James Houston, Wrists/Knee

• LG Tyler Smith, Knee

Kansas City Chiefs - OUT

• RG Trey Smith, Ankle

• TE Noah Gray, Concussion

• CB Chris Roland-Wallace, Back

Kansas City Chiefs - QUESTIONABLE

• None

Kansas City Chiefs - NO DESIGNATION

• LB Leo Chenal, Knee

• DE George Karlaftis, Thumb

• QB Patrick Mahomes, Groin

• RB Isaiah Pacheco, Knee

• WR Rashee Rice, Hamstring

• RT Jawaan Taylor, Knee

• WR Xavier Worthy, Ankle

This article originally appeared on Cowboys Wire: Cowboys-Chiefs Final injury report: Pickens status, Pro-Bowl OL ruled out